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"The Role of Entropy in the Modelling of Chromosome Conformation" by Prof. Dieter W. Heermann (4月11日,周三,上午11:00)
发表时间:2012-04-11 阅读次数:1183次

 

Title: The Role of Entropy in the Modelling of Chromosome Conformation

 

Speaker: Dieter W. Heermann
              Professor of Theoretical Physics at the University of Heidelberg

 

Time:  11:00 am, Wednesday, April 11

 

Venue: Room 1801, East Guanghua Tower

 

Abstract:

In vivo, chromosomes due to dynamic association with protein factors fold to form three-dimensional structures. Many experiments have paved the way to understand folding and the nuclear architecture of the genome for at least in eucaryotes but also beyond. Based on these experiments and models a fundamental understanding of the key principles that drive the physical organization has become possible through the concepts of loop and entropy. Using these concepts, models are now able to reproduce the results from several of the experiments.
 

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